Revolution Plus for Cats is an essential tool for cat owners who want to ensure their feline companions are well-protected from harmful parasites, both inside and outside the home. One of the most popular and effective products on the market today, Revolution Plus for Cats is a powerful, easy-to-apply treatment that offers comprehensive protection against a wide range of parasites, including fleas, ticks, heartworms, and more.
But with so many pet health products available, you may have questions about how Revolution Plus works, how safe it is, and what benefits it provides. In this guide, we’ll walk you through everything you need to know about Revolution Plus, including how it works, what it protects against, and how to use it effectively to keep your cat safe and healthy.
What is Revolution Plus for Cats?
Revolution Plus for Cats is a monthly topical treatment that provides broad-spectrum protection against a variety of external and internal parasites. It combines two active ingredients—selamectin and sarolaner—to offer effective and long-lasting protection. Revolution Plus is designed for cats 8 weeks and older, weighing at least 2.8 pounds (1.25 kg), making it suitable for most adult cats and kittens.
Revolution Plus is a prescription-only medication, meaning it should be obtained through a licensed veterinarian. The product is safe, effective, and easy to apply, ensuring that your cat remains protected from the most common parasites they may encounter.

What Does Revolution Plus Protect Against?
One of the major benefits of Revolution Plus is its multi-parasite protection, covering a wide range of external and internal parasites. This all-in-one solution simplifies your pet’s preventive care routine, making it a great choice for busy cat owners.
Here are the six types of parasites Revolution Plus helps protect against:
1. Fleas
Fleas are one of the most common and annoying parasites for both cats and humans. Revolution Plus kills adult fleas and prevents flea eggs from hatching. This helps control flea infestations in your home and reduces the likelihood of your cat becoming reinfested.
2. Ticks
Ticks are another significant health threat for cats, particularly if your feline spends time outdoors. Revolution Plus provides protection against three types of ticks:
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Black-legged ticks (Deer ticks)
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American dog ticks
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Gulf Coast ticks
By killing ticks on contact, Revolution Plus helps prevent tick-borne diseases, such as Lyme disease and anaplasmosis.
3. Heartworms
Heartworm disease is caused by parasitic worms transmitted by infected mosquitoes. Revolution Plus prevents heartworm disease, protecting your cat from the dangerous and often fatal effects of this condition.
4. Ear Mites
Ear mites are microscopic parasites that live in the ear canal and can cause intense itching, infection, and discomfort for your cat. Revolution Plus effectively treats and prevents ear mite infestations, helping to maintain your cat’s ear health.
5. Roundworms
Roundworms are intestinal parasites that can affect both kittens and adult cats. They can be transmitted through contaminated food, water, or feces. Revolution Plus kills roundworms, helping to protect your cat from potential digestive issues and discomfort.
6. Hookworms
Hookworms are another type of intestinal parasite that can cause anemia, weight loss, and digestive issues. Revolution Plus protects against hookworms, ensuring your cat’s gastrointestinal system remains free of these harmful parasites.
How Does Revolution Plus Work?
Once applied to the skin at the back of your cat’s neck, Revolution Plus is absorbed into the bloodstream, providing systemic protection against both external and internal parasites. The active ingredients, selamectin and sarolaner, work together to target different aspects of parasite physiology.
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Selamectin: This ingredient works by disrupting the nervous system of parasites, leading to their paralysis and death. It helps control fleas, ear mites, and certain internal parasites, such as roundworms and hookworms.
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Sarolaner: This ingredient is specifically designed to target ticks and fleas. It works by inhibiting the activity of neurotransmitters, causing paralysis and death in ticks and fleas that come into contact with it.
The combination of these two ingredients provides both immediate relief from existing infestations and ongoing protection for up to 30 days. This makes Revolution Plus a convenient, once-a-month treatment that simplifies your cat’s parasite prevention routine.
How to Apply Revolution Plus for Cats
The application process for Revolution Plus is simple and straightforward. Here’s a step-by-step guide:
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Remove the applicator from the packaging.
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Part your cat’s fur at the base of the neck until the skin is visible.
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Place the tip directly on the skin and squeeze out the entire contents of the applicator.
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Do not massage the solution into your cat’s fur; it will be absorbed into the skin on its own.
Important Notes:
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Avoid bathing your cat for at least 24 hours after applying Revolution Plus to ensure maximum effectiveness.
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Make sure to apply the solution to bare skin, not on the fur, as it needs to be absorbed to work properly.
How Often Should You Use Revolution Plus?
Revolution Plus should be applied once every 30 days for continuous protection. Setting a reminder for a monthly application can help ensure that you don’t forget to treat your cat. Since Revolution Plus provides comprehensive parasite protection, it’s easy to keep your cat safe from various parasites with minimal effort.
Is Revolution Plus Safe for Cats?
Revolution Plus is generally safe when used as directed. It has been thoroughly tested in clinical trials and is FDA-approved for use in cats. However, as with any medication, there may be some mild side effects, including:
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Hair loss or irritation at the application site
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Mild itching or redness
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Digestive upset, such as vomiting or diarrhea (rare)
If you notice anything unusual or concerning after applying Revolution Plus, it’s best to consult your vet immediately. Severe reactions to Revolution Plus are rare, but it’s always a good idea to keep an eye on your cat for the first few hours after application.
Revolution Plus vs. Revolution: What’s the Difference?
Both Revolution and Revolution Plus are flea and parasite treatments for cats, but there are some important differences between them. Revolution Plus offers broader protection because it includes sarolaner, which provides tick protection that Revolution does not. Revolution is a great option if you’re primarily concerned about flea control, but for those who live in tick-prone areas, Revolution Plus is the superior choice.
Here’s a comparison:
| Feature | Revolution | Revolution Plus |
|---|---|---|
| Flea & Tick Protection | Fleas only | Fleas + Ticks |
| Heartworm Prevention | ✅ | ✅ |
| Roundworm & Hookworm | ✅ | ✅ |
| Ear Mite Control | ✅ | ✅ |
| Tick Protection | ❌ | ✅ |
A Comprehensive Solution for Your Cat’s Parasite Protection
Revolution Plus for Cats offers one of the most effective and convenient solutions for protecting your cat against a wide range of parasites. Whether your cat is an indoor-only pet or spends time outdoors, Revolution Plus ensures comprehensive protection against fleas, ticks, heartworms, and other common parasites.
By incorporating Revolution Plus into your cat’s monthly routine, you can rest assured that they are receiving top-tier protection from harmful pests that can cause discomfort, disease, and even life-threatening conditions. As always, be sure to consult with your vet to determine if Revolution Plus is the right fit for your cat’s needs.